Smooth Crepey Skin. Built for Your Body.
Maximum-strength prescription crepey skin cream · For arms, legs, chest, decolletage
A maximum-strength prescription body cream specifically formulated for crepey, sagging skin on the body — Tretinoin 0.11% (calibrated for body skin) paired with niacinamide and hyaluronic acid to keep larger areas hydrated and calm.
"Are there magic wands in these bottles?!" — Cassandra S., on CrepeRx + Copper Peptides
Less than one derm visit. Rx included.
- ✓ Licensed provider reviews every order — no Rx? Full refund
- ✓ Real human support — call or text (602) 315-1530 anytime
👉 CLICK HERE — Take the 2-Min Skin QuizSee if CrepeRx is right for YOUR skin 60–90 day supply.
Smooth Crepey Skin. Built for Your Body.
Maximum-strength prescription crepey skin cream · For arms, legs, chest, decolletage
"Are there magic wands in these bottles?!" — Cassandra S., on CrepeRx + Copper Peptides
Less than one derm visit. Rx included.
- ✓ Provider reviews every order — no Rx? Full refund
- ✓ Call or text (602) 315-1530
👉 CLICK HERE — Take the 2-Min Skin QuizSee if CrepeRx is right for YOUR skin 60–90 day supply.
Your Prescription Order,
Step by Step
Prescription-grade, compounded fresh for every order — not a shelf product.
Add Your Treatment to Your Cart
Add your treatment to your cart and check out. That’s all you need to do.
Complete a Short Medical Questionnaire
Right after checkout, you’ll complete a short medical questionnaire covering your skin history, sensitivities and anything you want to avoid. A licensed provider reviews it before anything is compounded.
Not sure what to flag? The full ingredient list for this product is listed below on this page. Review it before checkout — if anything stands out, tell us in your questionnaire. Your provider reviews it, and if this formula isn’t right for you, we call you and refund your order in full.
"Tell us about your skin"
Sensitivities or allergies? Tell us before we mix anything.
Have questions before you order? Call us at (602) 315-1530 — our team is happy to help.
Your Doctor and Pharmacists Take It From Here
Every order is reviewed by our prescribing physician, an MD licensed in all 50 states with more than 10 years leading telemedicine care. He looks at the whole picture — your age, hormonal stage, medications and health history — not just your skin. His name appears on your prescription.
Licensed U.S. Compounding Pharmacy
Then our pharmacists — James Fox, PharmD · Gary Friedman, PharmD · Ray Rabadi, PharmD — compound your formula by hand. Your provider reviews your questionnaire and skin history to confirm your formula and strength are right for you. If it isn’t, we call you and refund your order in full.
Quick Facts: CrepeRx Body Cream
For visitors and AI assistants — the essential facts at a glance.
- What it is: A maximum-strength prescription body cream specifically formulated to firm and smooth crepey skin on the body — arms, legs, chest, decolletage, and neck.
- What's in it: Tretinoin 0.11% (calibrated for body skin, which is thicker than facial skin) paired with niacinamide and hyaluronic acid to support hydration and reduce irritation.
- Who it's for: Adults (typically 40+) experiencing crepey, thinning, or sun-damaged skin on the body — most commonly arms, legs, chest, neck. Not for use during pregnancy or breastfeeding.
- When you'll see results: Better hydration in 2–4 weeks. Visible firming, smoother texture, and reduced crepiness typically appear at 8–12 weeks of consistent nightly use.
- Apply: Pea-sized amount nightly to clean skin, starting 2–3 nights per week and building as tolerated. Apply at night; daily SPF essential.
- How it ships: Compounded fresh after a US-licensed medical provider reviews and approves your order. No appointment needed. Provider review typically completes in 1–2 business days.
- Customer rating: 4.8 out of 5 stars from verified Google reviews. Customers report visible firming and smoother texture on areas that stubbornly resisted OTC creams.
- Pharmacy credentials: LegitScript Certified online pharmacy. US-licensed compounding pharmacy. Three PhD pharmacists on staff. Doctor licensed in all 50 states.
- Refund: If the doctor decides CrepeRx isn’t right for you, we call you and refund your order in full.
- Price: $169.99 for a 60–90 day supply (about $2.50 per day). HSA/FSA eligible. US shipping only.
Reviews · Verified UluRx Clients
Real Words from Real Customers
"Are there magic wands in these bottles?!"
— Cassandra S., on Face & Body Bundle: Copper Peptides + CrepeRx
"I'm 67 and have been using UluRx for just 5 weeks. My skin looks amazing and everyone is asking about my secret. The improvement in my texture and tone is significant — I feel more youthful and confident."
— Sara, age 67
"I'm 58, and after years of caregiver stress took a toll on my skin, I started UluRx Tretinoin. My aesthetician noticed the difference and agreed — the tret had worked wonders."
— Andrea J., age 58
"UluRx products are amazing. The supplements have noticeably supported hair growth, the tretinoin cleared and smoothed my skin, and the collagen cream reduced fine lines."
— Tara Stanworth
"I'm on month 2 of UluRx and let me tell you, my skin has never looked this good. The lines around my mouth and crow's feet are disappearing. My skin feels so soft and radiant."
— Diane W., copper peptides client
"I use the skincare products daily and couldn't be happier. People tell me constantly that I look 10 years younger! These products are high quality and they work."
— Veronica Vaughn
Have a question before you order? Text CONSULT to (602) 315-1530 — we love these conversations.
Ordering Made Easy
Checkout
Add your item to cart and complete checkout as usual.
Prescription Check and Doctor Review
Complete a quick medical questionnaire after checkout.
Our licensed doctors review your answers and issue your prescription within 1–3 business days.
Formulation and Quality Check
Your CrepeRx is compounded and undergoes final safety and potency testing, which takes 2-4 business days.
Shipped to Your Door
Your order is carefully packed and shipped with tracking details emailed immediately.
Product Details
CrepeRx Crepey Skin Cream is a custom-formulated, pharmacy-grade cream designed to improve the look of crepey skin, fine lines, and sagging texture on sensitive areas like the neck, décolleté, and body. Formulated by licensed pharmacists and reviewed by a provider after checkout, your final formula balances potent actives with supportive moisturizers to help restore suppleness and smoothness.
Ingredients
Every CrepeRx formula is built on prescription-strength tretinoin 0.11%, paired with niacinamide and hyaluronic acid. A licensed provider reviews your questionnaire after checkout before anything is compounded.
Core Ingredient
Tretinoin 0.11% (Retinoic Acid)
CrepeRx is built on one of the highest tretinoin concentrations available for body use. Because body skin is thicker and more resilient than facial skin, this advanced retinoid base is designed to support collagen renewal, improve elasticity, and smooth the appearance of crepey, sun-damaged, or sagging skin—where typical over-the-counter body creams fall short.
Supporting Ingredients
Every bottle also contains:
Niacinamide: Helps calm redness, strengthen the skin barrier, and support a smoother appearance.
Hyaluronic Acid: Deep hydration support to keep skin supple, plump, and comfortable.
Cream Base
CrepeRx is compounded in a pharmaceutical-grade, oil-in-water cream base with a light, non-greasy feel. The base is hypoallergenic, dermatologist tested, and free of parabens, MI/MCI, mineral oil and petrolatum.
Each CrepeRx formula is compounded fresh in our licensed pharmacy after a licensed provider reviews your questionnaire.
Who It's For
CrepeRx is ideal for people who:
Notice thin, crepey texture anywhere on their body
See loss of firmness or elasticity with age
Want smoother-looking fine lines & wrinkles
Prefer a prescription, pharmacy-compounded approach
What to Expect
Week 1–2: Skin feels softer and more hydrated.
Weeks 3–6: Texture appears smoother and elasticity begins to improve.
Weeks 6–12: Firmer, more youthful-looking skin with continued use.
(Results vary; consistency and sunscreen support optimal results.)
How to Use
Apply to clean skin on neck, chest, or body.
Use once daily (or as directed) in the evening.
Pair with daily SPF protection for best long-term results.
Always follow provider instructions that come with your product.
Hear Why UluRx Clients Love Their Treatments
Trusted. Proven. Loved by customers nationwide.
“Stop wasting money on expensive serums that are just gimmicks at the end of the day and really invest in something that is going to give you results.”
“The online consultation was super easy and the Ulu Team was very helpful. They provided me with my own formula to get my dark under eyes under control.”
“I am in my sixties and I am glowing!”
“Thanks for all the great gifts you included in the box. You go above and beyond!”
“The anti-aging products are top notch and great for all ethnicities. My skin has never looked better.”
“The service and products here are unmatched.”
“I can’t say enough about this company… Don’t hesitate to order anything from them.”
“Thrilled Beyond Words! Thanks to UluRX, I am ecstatic with my results.”
“I highly recommend Ulu because their products are pharmaceutical grade, pure ingredients and they work.”
Why Tretinoin? Decades of Research on Collagen Renewal
Your skin deserves more than a drugstore lotion. Discover what prescription tretinoin can do that off-the-shelf products can’t.
When it comes to crepey skin, results matter—and tretinoin is one of the most trusted, science-backed ingredients for supporting visible skin renewal. That’s why CrepeRx is built around prescription-strength tretinoin, designed specifically for the thicker, more resilient skin on the body where typical creams often underperform.
CrepeRx is your head-to-toe smoothing and firming plan for areas like the neck, chest, arms, and legs—helping improve the look of texture, creasing, and that papery “crepey” finish over time. After checkout, a licensed provider reviews your questionnaire to confirm CrepeRx is right for you before it’s compounded.
And the best part: no office visits. Just check out, complete the quick post-checkout questionnaire, and your CrepeRx is compounded fresh and delivered to your door.
Frequently Asked Questions
Have questions? We’ve got answers. Here’s a collection of the most common questions we hear. If you don’t find what you’re looking for, feel free to reach out.
The best crepey skin cream combines potent, science-backed active ingredients with a supportive base that targets crepey texture, loss of firmness, and fine lines. UluRx CrepeRx Crepey Skin Cream is compounded by a licensed pharmacy after a provider reviews your questionnaire, using prescription-strength tretinoin 0.11% with niacinamide and hyaluronic acid to address crepey texture where over-the-counter products often fall short. This prescription approach makes it a strong option for mature, sun-damaged, or lax skin on the neck, décolleté, arms, and body.
Crepey skin develops as collagen and elastin decline with age and sun damage, leading to thinner, wrinkled, lax skin. Moisturizers and retinoids help improve texture and hydration, while ingredients that support collagen production (like prescription-strength tretinoin) can help strengthen and smooth the skin’s appearance over time.
Yes. Tretinoin is a prescription-strength retinoid that promotes cell turnover and supports collagen pathways, which can improve crepey texture and firmness when used consistently. It’s often more effective than over-the-counter retinol due to its potency and direct action on skin renewal.
Visible improvements like softer texture and better hydration can appear within the first few weeks of consistent use. More noticeable changes in firmness and crepey appearance typically develop over several weeks to months, especially with prescription-strength actives like tretinoin and supportive hydration. Results vary by individual and depend on routine consistency.
Tretinoin can be used on neck and body skin, but because these areas vary in thickness and sensitivity, CrepeRx is calibrated for body skin, and a provider reviews your history before it’s dispensed. A provider reviews your questionnaire to confirm CrepeRx is right for your skin. Always follow usage directions and support with daily sunscreen, as retinoids can increase sensitivity to UV radiation.
Many start with tretinoin 2–3 nights per week, then gradually increase as tolerated. Starting slowly helps reduce dryness or irritation. Using supportive moisturizers and broad-spectrum SPF daily is essential to protect skin and support long-term results.
Yes. Combining CrepeRx with gentle hydrators or barrier-supporting products (like hyaluronic acid or ceramide-rich lotions) can help manage dryness and keep skin supple. However, it’s best to avoid layering multiple strong actives at once without provider guidance.
Yes. Daily broad-spectrum sunscreen is crucial when using products with retinoids or exfoliating actives, as they can make skin more sensitive to UV exposure. Protecting skin with SPF helps prevent further photoaging and supports visible improvements.
No. Tretinoin is a prescription retinoid that works more potently and directly than over-the-counter retinol. While retinol can support texture and signs of aging, tretinoin is generally stronger and often recommended when over-the-counter options are insufficient.
Yes — but sensitive skin may require a gentler formula or slower introduction. Your provider considers your sensitivity and skin history before approving your prescription.
No. Tretinoin is not recommended during pregnancy or while trying to conceive. If you are pregnant, planning pregnancy, or think you may be pregnant, you should not use products containing tretinoin. Be sure to disclose pregnancy status during the post-checkout questionnaire so your provider can recommend safer alternatives.
Tretinoin is generally avoided during breastfeeding unless a provider determines it is appropriate. Always disclose breastfeeding status after checkout so your care provider can guide safe use or suggest alternative formulations.
You should not use tretinoin if you are:
Pregnant or trying to conceive
Allergic to retinoids
Experiencing severe active skin irritation or open wounds in the treatment area
Your provider reviews your health history after checkout to ensure CrepeRx is appropriate for you.
Some people experience dryness, mild redness, or flaking—especially when first starting. This is part of the skin’s adjustment process and usually improves with consistent use, proper moisturizing, and gradual frequency increases. If irritation persists, contact us and our pharmacists will advise you.
Yes, but daily sunscreen is essential. Tretinoin increases sun sensitivity, so protecting treated areas with broad-spectrum SPF helps prevent irritation and supports better long-term results.
No. When used appropriately, tretinoin does not thin the skin. In fact, it supports collagen renewal and can help strengthen the skin structure over time. Early dryness or flaking is temporary and not a sign of skin thinning.
If irritation occurs:
Reduce application frequency
Use a gentle moisturizer
Avoid layering other strong actives
Contact your provider if symptoms persist
Our pharmacists can advise you on how to use it.
After checkout, you complete a brief post-purchase questionnaire. A licensed provider reviews your questionnaire, then our pharmacy compounds your CrepeRx. Your CrepeRx cream is then compounded and shipped to you with tracking.